Targeted Temperature Management in Cardiac Arrest: An Updated Narrative Review.

ABSTRACT: The established benefits of cooling along with development of sophisticated methods to safely and precisely induce, maintain, monitor, and reverse hypothermia have led to the development of targeted temperature management (TTM). Early trials in human subjects showed that hypothermia conferred better neurological outcomes when compared to normothermia among survivors of cardiac arrest, leading to guidelines recommending targeted hypothermia in this patient population. Multiple studies have sought to explore and compare the benefit of hypothermia in various subgroups of patients, such as survivors of out-of-hospital cardiac arrest versus in-hospital cardiac arrest, and survivors of an initial shockable versus non-shockable rhythm. Larger and more recent trials have shown no statistically sig

SUBMITTER: Belur AD 

PROVIDER: S-EPMC9986171 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature