Effects of systemic inflammation and frailty on survival in elderly cancer patients: Results from the INSCOC study.

ABSTRACT:

Background

Frailty and systemic inflammation are parameters, which are easy to evaluate, can be used to predict disease outcomes, and are potentially modifiable. The combination of frailty and inflammation-based data may help identify elderly cancer patients predisposed to adverse clinical outcomes. The aim of this study was to examine the association of systemic inflammation and frailty at admission, and to determine whether these risk factors interact and may predict the survival of elderly cancer patients.

Methods

A prospective Investigation on Nutrition Status and Clinical Outcome of Common Cancers (INSCOC) with 5,106 elderly cancer patients admitted from 2013 through 2020 was included in this study. The primary marker of inflammation was the neutrophil-to-lymphocyte rat

SUBMITTER: Zhang Q 

PROVIDER: S-EPMC9986529 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature