Cardiovascular Diseases, Medications, and ALS: A Population-Based Case-Control Study.

ABSTRACT:

Introduction

We investigated the associations between antecedent all-cause CVD diagnoses, cause-specific CVD diagnosis, and CVD medication prescriptions with the risk of developing amyotrophic lateral sclerosis (ALS).

Materials and methods

We conducted a population-based case-control study of U.S. Medicare enrollees from 2006 to 2013. The final sample included 3,714 incident ALS cases and 18,570 controls (matched on age, sex, enrollment length, and county). Information was collected from Medicare Parts A, B, and D administrative claims data on hypertension, ischemic heart disease, heart failure, acute myocardial infarction, atrial fibrillation, prescriptions of angiotensin-converting enzyme inhibitors, angiotensin II receptors blockers, calcium channel blockers, beta blocker

SUBMITTER: Abdel Magid HS 

PROVIDER: S-EPMC9986836 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature