Characterizing the Self-Assembly Properties of Monoolein Lipid Isosteres.

ABSTRACT: Living cells feature lipid compartments which exhibit a variety of shapes and structures that assist essential cellular processes. Many natural cell compartments frequently adopt convoluted nonlamellar lipid architectures that facilitate specific biological reactions. Improved methods for controlling the structural organization of artificial model membranes would facilitate investigations into how membrane morphology affects biological functions. Monoolein (MO) is a single-chain amphiphile which forms nonlamellar lipid phases in aqueous solution and has wide applications in nanomaterial development, the food industry, drug delivery, and protein crystallization. However, even if MO has been extensively studied, simple isosteres of MO, while readily accessible, have seen limited characteriza

SUBMITTER: Fracassi A 

PROVIDER: S-EPMC9986874 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature