Different lymph node dissection ranges during radical prostatectomy for patients with prostate cancer: a systematic review and network meta-analysis.

ABSTRACT:

Objective

The purpose of this network meta-analysis was to compare the effectiveness and adverse effects of limited, standard, extended, and super-extended pelvic lymph node dissection (PLND) following radical prostatectomy.

Methods

This study followed the PRISMA 2020 statement. Clinical trials were searched from three electronic databases, including PubMed, the Cochrane Library, and Embase from the database's inception to April 5, 2022. The lymph node-positive rate, biochemical recurrence-free rate, lymphocele rate, thromboembolic rate, and overall complication rate were compared by meta-analysis. Data analyses were performed using R software based on the Bayesian framework.

Results

Sixteen studies involving 15,269 patients were included. All 16 studies compared the

SUBMITTER: Zhang X 

PROVIDER: S-EPMC9987045 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature