Customized biofilm device for antibiofilm and antibacterial screening of newly developed nanostructured silver and zinc coatings.

ABSTRACT:

Background

Bacterial colonisation on implantable device surfaces is estimated to cause more than half of healthcare-associated infections. The application of inorganic coatings onto implantable devices limits/prevents microbial contaminations. However, reliable and high-throughput deposition technologies and experimental trials of metal coatings for biomedical applications are missing. Here, we propose the combination of the Ionized Jet Deposition (IJD) technology for metal-coating application, with the Calgary Biofilm Device (CBD) for high-throughput antibacterial and antibiofilm screening, to develop and screen novel metal-based coatings.

Results

The films are composed of nanosized spherical aggregates of metallic silver or zinc oxide with a homogeneous and highly rough su

SUBMITTER: Ghezzi D 

PROVIDER: S-EPMC9987098 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature