Asthma occurrence in children and early life systemic antibiotic use: an incidence density study.

ABSTRACT:

Background

Results of studies evaluating the relationship between asthma occurrence and early life antibiotic use have been conflicting. The aim of this study was to investigate the relationship between occurrence of asthma in children and systemic antibiotic use in the first year of life based on an incidence density study with careful consideration of the temporal aspects of the determinant-outcome relationship.

Methods

We conducted an incidence density study nested in a data collection project with information on 1128 mother-child pairs. Systemic antibiotic use in the first year of life was defined as excessive (≥ 4 courses) vs. non-excessive (< 4 courses) use based on information from weekly diaries. Events (cases) were defined as the first parent-reported occurrence of

SUBMITTER: Bentouhami H 

PROVIDER: S-EPMC9987135 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature