The relationship between metabolic dysfunction-associated fatty liver disease and the incidence rate of extrahepatic cancer.

ABSTRACT:

Background

The associations between metabolic dysfunction-associated fatty liver disease (MAFLD) and cancer development, especially extrahepatic cancers, are unknown. The aims of the current study were to investigate the cancer incidence rates of MAFLD and analyze the associations between MAFLD and the development of cancers.

Methods

This historical cohort study included participants who underwent ultrasonographic detection of hepatic steatosis at a tertiary hospital in China from January 2013 to October 2021. MAFLD was diagnosed in accordance with The International Expert Consensus Statement. Cox proportional hazards regression modeling was used to assess the associations between MAFLD and the development of cancers.

Results

Of the 47,801 participants, 16,093

SUBMITTER: Wei S 

PROVIDER: S-EPMC9987419 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature