Learning-Induced Odor Modulation of Neuronal Activity in Auditory Cortex.

ABSTRACT: Sensory cortices, even of primary regions, are not purely unisensory. Rather, cortical neurons in sensory cortex show various forms of multisensory interactions. While some multisensory interactions naturally co-occur, the combination of others will co-occur through experience. In real life, learning and experience will result in conjunction with seemingly disparate sensory information that ultimately becomes behaviorally relevant, impacting perception, cognition, and action. Here we describe a novel auditory discrimination task in mice, designed to manipulate the expectation of upcoming trials using olfactory cues. We show that, after learning, female mice display a transient period of several days during which they exploit odor-mediated expectations for making correct decisions. Using tw

SUBMITTER: Gilday OD 

PROVIDER: S-EPMC9987573 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature