Maternal Western-style diet reduces social engagement and increases idiosyncratic behavior in Japanese macaque offspring.

ABSTRACT: Recent evidence in humans and animals indicates an association between maternal obesity and offspring behavioral outcomes. In humans, increased maternal body mass index has been linked to an increased risk of children receiving a diagnosis of early-emerging neurodevelopmental disorders such as Attention Deficit/Hyperactivity Disorder (ADHD) and/or Autism Spectrum Disorder (ASD). However, a limited number of preclinical studies have examined associations between maternal Western-Style Diet (mWSD) exposure and offspring social behavior. To our knowledge, this is the first study to investigate relationships between mWSD exposure and social behavior in non-human primates. Since aberrant social behavior is a diagnostic criterion for several neurodevelopmental disorders, the current study focuse

SUBMITTER: Mitchell AJ 

PROVIDER: S-EPMC9987715 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature