Stem cell and tissue engineering approaches in pressure ulcer treatment.

ABSTRACT:

Context

Pressure ulcers or injuries, arise from ischemic damage to soft tissues induced by unrelieved pressure over a bony prominence. They are usually difficult to treat with standard medical therapy and often they recur. In the search for better treatment options, promising alternative forms of treatment are today emerging. Within the field of regenerative medicine, ongoing research on advanced therapies seeks to develop medicinal products based on gene therapy, somatic cell therapy, tissue-engineering and combinations of these.

Objective

The main objective is to perform an overview of experimental and clinical developments in somatic cell therapy and tissue engineering targeting the treatment of pressure injuries.

Methods

Searching terms as "PRESSURE ULCER", "STEM

SUBMITTER: Perez-Lopez S 

PROVIDER: S-EPMC9987762 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature