Hepatocellular carcinoma presentation and prognosis among Nigerian adults with and without HIV.

ABSTRACT:

Introduction

Hepatocellular carcinoma (HCC) is an increasing cause of mortality in Nigeria among persons with HIV (PLH), as access to antiretroviral therapy (ART) improves. In this study we describe clinical, radiological, and laboratory characteristics in Nigerian adults with HCC, with and without HIV, and examine how HIV impacts survival.

Methods

This prospective observational study was conducted between August 2018 and November 2021 at two Nigerian hospitals [Jos University Teaching Hospital (JUTH) and Lagos University Teaching Hospital (LUTH)]. Subjects ≥18 years with HCC diagnosed according to American Association for the Study of Liver Diseases (AASLD) criteria were included. Baseline characteristics were compared, and Kaplan-Meier curves were generated to estimate sur

SUBMITTER: Davwar PM 

PROVIDER: S-EPMC9987777 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature