Intensive Care and Organ Support Related Mortality in Patients With COVID-19: A Systematic Review and Meta-Analysis.

ABSTRACT: To perform a systematic review and meta-analysis to generate estimates of mortality in patients with COVID-19 that required hospitalization, ICU admission, and organ support.

Data sources

A systematic search of PubMed, Embase, and the Cochrane databases was conducted up to December 31, 2021.

Study selection

Previously peer-reviewed observational studies that reported ICU, mechanical ventilation (MV), renal replacement therapy (RRT) or extracorporeal membrane oxygenation (ECMO)-related mortality among greater than or equal to 100 individual patients.

Data extraction

Random-effects meta-analysis was used to generate pooled estimates of case fatality rates (CFRs) for in-hospital, ICU, MV, RRT, and ECMO-related mortality. ICU-related mortality was additionally analyzed by

SUBMITTER: Chandel A 

PROVIDER: S-EPMC9988289 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature