The breast milk and childhood gastrointestinal microbiotas and disease outcomes: a longitudinal study.

ABSTRACT:

Background

We aimed to characterize breast milk microbiota and define associations with saliva and fecal microbiota and selected diseases in preschool children.

Methods

In a longitudinal cohort study, the microbiotas from breast milk, mouth, and fecal samples were characterized by 16S rRNA gene sequencing. Questionnaires and medical records provided information on demographics, medical, and dental data.

Results

The phylogeny in breast milk, saliva swabs, and feces differed at all levels (p < 0.0003), though all harbored species in Streptococcus, Veillonella, and Haemophilus. Species richness was highest in breast milk with increasing resemblance with the oral swab microbiota by increasing age. Caries-affected children at age 5 had been fed breast milk with tenfold hig

SUBMITTER: Lif Holgerson P 

PROVIDER: S-EPMC9988688 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature