Physical Activity Is Associated With Macular Thickness: A Multi-Cohort Observational Study.

ABSTRACT:

Purpose

To assess the association between physical activity and spectral-domain optical coherence tomography (SD-OCT)-measured rates of macular thinning in an adult population with primary open-angle glaucoma.

Methods

The correlation between accelerometer-measured physical activity and rates of macular ganglion cell-inner plexiform layer (GCIPL) thinning was measured in 735 eyes from 388 participants of the Progression Risk of Glaucoma: RElevant SNPs with Significant Association (PROGRESSA) study. The association between accelerometer-measured physical activity and cross-sectional SD-OCT macular thickness was then assessed in 8862 eyes from 6152 participants available for analysis in the UK Biobank who had SD-OCT, ophthalmic, comorbidity, and demographic data.

Results

SUBMITTER: Berry EC 

PROVIDER: S-EPMC9988706 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature