Complexity analysis of heartbeat-related signals in brain MRI time series as a potential biomarker for ageing and cognitive performance.

ABSTRACT: Getting older affects both the structure of the brain and some cognitive capabilities. Until now, magnetic resonance imaging (MRI) approaches have been unable to give a coherent reflection of the cognitive declines. It shows the limitation of the contrast mechanisms used in most MRI investigations, which are indirect measures of brain activities depending on multiple physiological and cognitive variables. However, MRI signals may contain information of brain activity beyond these commonly used signals caused by the neurovascular response. Here, we apply a zero-spin echo (ZSE) weighted MRI sequence, which can detect heartbeat-evoked signals (HES). Remarkably, these MRI signals have properties only known from electrophysiology. We investigated the complexity of the HES arising from this sequ

SUBMITTER: Lopez Perez D 

PROVIDER: S-EPMC9988766 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature