Regulatory mechanisms of microRNAs in endocrine disorders and their therapeutic potential.

ABSTRACT: MicroRNAs (miRNAs) are small endogenous non-coding RNA molecules capable of regulating gene expression at the post-transcriptional level either by translational inhibition or mRNA degradation and have recently been importantly related to the diagnosis and prognosis of the most relevant endocrine disorders. The endocrine system comprises various highly vascularized ductless organs regulating metabolism, growth and development, and sexual function. Endocrine disorders constitute the fifth principal cause of death worldwide, and they are considered a significant public health problem due to their long-term effects and negative impact on the patient's quality of life. Over the last few years, miRNAs have been discovered to regulate various biological processes associated with endocrine disorde

SUBMITTER: Ledesma-Pacheco SJ 

PROVIDER: S-EPMC9989203 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature