Development and validation of an echocardiographic algorithm to predict long-term mitral and tricuspid regurgitation progression.

ABSTRACT:

Aims

Prediction of mitral (MR) and tricuspid (TR) regurgitation progression on transthoracic echocardiography (TTE) is needed to personalize valvular surveillance intervals and prognostication.

Methods and results

Structured TTE report data at Beth Israel Deaconess Medical Center, 26 January 2000-31 December 2017, were used to determine time to progression (≥1+ increase in severity). TTE predictors of progression were used to create a progression score, externally validated at Massachusetts General Hospital, 1 January 2002-31 December 2019. In the derivation sample (MR, N = 34 933; TR, N = 27 526), only 5379 (15.4%) individuals with MR and 3630 (13.2%) with TR had progression during a median interquartile range) 9.0 (4.1-13.4) years of follow-up. Despite wide inter-individua

SUBMITTER: Strom JB 

PROVIDER: S-EPMC9989598 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature