Reduced emergent character of neural dynamics in patients with a disrupted connectome.

ABSTRACT: High-level brain functions are widely believed to emerge from the orchestrated activity of multiple neural systems. However, lacking a formal definition and practical quantification of emergence for experimental data, neuroscientists have been unable to empirically test this long-standing conjecture. Here we investigate this fundamental question by leveraging a recently proposed framework known as "Integrated Information Decomposition," which establishes a principled information-theoretic approach to operationalise and quantify emergence in dynamical systems - including the human brain. By analysing functional MRI data, our results show that the emergent and hierarchical character of neural dynamics is significantly diminished in chronically unresponsive patients suffering from severe brai

SUBMITTER: Luppi AI 

PROVIDER: S-EPMC9989666 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature