Cortical neuronal assemblies coordinate with EEG microstate dynamics during resting wakefulness.

ABSTRACT: The disruption of cortical assembly activity has been associated with anesthesia-induced loss of consciousness. However, the relationship between cortical assembly activity and the variations in consciousness associated with natural vigilance states remains unclear. Here, we address this by performing vigilance state-specific clustering analysis on 2-photon calcium imaging data from the sensorimotor cortex in combination with global electroencephalogram (EEG) microstate analysis derived from multi-EEG signals obtained over widespread cortical locations. We report no difference in the structure of assembly activity during quiet wakefulness (QW), non-rapid eye movement sleep (NREMs), or REMs, despite the latter two vigilance states being associated with significantly reduced levels of consci

SUBMITTER: Boyce R 

PROVIDER: S-EPMC9989822 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature