Effectiveness of eradication therapy for Helicobacter pylori infection in Africa: a systematic review and meta-analysis.

ABSTRACT:

Background

The effectiveness of Helicobacter pylori (H. pylori) eradication depends on the treatment protocol. This study investigates the H. pylori eradication rate in Africa using the best available evidence from databases.

Methods

Databases were searched and results were pooled together. Heterogeneity between studies was assessed using I² test statistics. Stata version 13 software was employed to compute the pooled eradication rate. In the subgroup analysis comparison, the finding is considered significant when the confidence intervals did not overlap.

Results

Twenty-two studies from 9 African countries with a total population of 2,163 were included in this study. The pooled eradication rate of H. pylori was 79% (95% CI: 75%-82%), heterogeneity (I^2<

SUBMITTER: Fekadu S 

PROVIDER: S-EPMC9990047 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature