Hyperoxemia after reperfusion in cardiac arrest patients: a potential dose-response association with 30-day survival.

ABSTRACT:

Background

Hyperoxemia may aggravate reperfusion brain injury after cardiac arrest. The aim of this study was to study the associations between different levels of hyperoxemia in the reperfusion period after cardiac arrest and 30-day survival.

Methods

Nationwide observational study using data from four compulsory Swedish registries. Adult in- and out-of-hospital cardiac arrest patients admitted to an ICU, requiring mechanical ventilation, between January 2010 and March 2021, were included. The partial oxygen pressure (PaO₂) was collected in a standardized way at ICU admission (± one hour) according to the simplified acute physiology score 3 reflecting the time interval with oxygen treatment from return of spontaneous circulation to ICU admission. Subsequently, pat

SUBMITTER: Awad A 

PROVIDER: S-EPMC9990272 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature