Association between obstructive sleep apnoea and cancer: a cross-sectional, population-based study of the DISCOVERY cohort.

ABSTRACT:

Objectives

Nocturnal hypoxia in obstructive sleep apnoea (OSA) is a potential risk factor for cancer. We aimed to investigate the association between OSA measures and cancer prevalence in a large national patient cohort.

Design

Cross-sectional study.

Settings

44 sleep centres in Sweden.

Participants

62 811 patients from the Swedish registry for positive airway pressure (PAP) treatment in OSA, linked to the national cancer registry and national socioeconomic data (the course of DIsease in patients reported to Swedish CPAP, Oxygen and VEntilator RegistrY cohort).

Outcome measures

After propensity score matching for relevant confounders (anthropometric data, comorbidities, socioeconomic status, smoking prevalence), sleep apnoea severity, measured as Apnoea-

SUBMITTER: Palm A 

PROVIDER: S-EPMC9990651 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature