CT Scan-Derived Muscle, But Not Fat, Area Independently Predicts Mortality in COVID-19.

ABSTRACT:

Background

COVID-19 has demonstrated a highly variable disease course, from asymptomatic to severe illness and eventually death. Clinical parameters, as included in the 4C Mortality Score, can predict mortality accurately in COVID-19. Additionally, CT scan-derived low muscle and high adipose tissue cross-sectional areas (CSAs) have been associated with adverse outcomes in COVID-19.

Research question

Are CT scan-derived muscle and adipose tissue CSAs associated with 30-day in-hospital mortality in COVID-19, independent of 4C Mortality Score?

Study design and methods

This was a retrospective cohort analysis of patients with COVID-19 seeking treatment at the ED of two participating hospitals during the first wave of the pandemic. Skeletal muscle and adipose tissue CSAs w

SUBMITTER: van Bakel SIJ 

PROVIDER: S-EPMC9990885 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature