Serum fetuin-A is decreased in cirrhotic patients with Wilson's disease.

ABSTRACT:

Introduction

Wilson's disease may lead to cirrhosis, but timely medical treatment could slow down its progression. Clinical markers helping early diagnosis are essential. Decreased fetuin-A concentration has been reported in cirrhosis of different etiologies. The aim of this study was to investigate whether decreased serum fetuin-A concentration could identify patients with Wilson's disease who developed cirrhosis.

Materials and methods

In this cross-sectional study we determined the serum fetuin-A concentration of 50 patients with Wilson's disease. We analyzed the data of patients with liver involvement, comparing cirrhotic and non-cirrhotic patients.

Results

Among patients with liver involvement those with cirrhosis had significantly lower fetuin-A and albumin level

SUBMITTER: Voros K 

PROVIDER: S-EPMC9990947 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature