Coronary Obstruction From TAVR in Native Aortic Stenosis: Development and Validation of Multivariate Prediction Model.

ABSTRACT:

Background

Transcatheter aortic valve replacement (TAVR)-related coronary artery obstruction prediction remains unsatisfactory despite high mortality and novel preventive therapies.

Objectives

This study sought to develop a predictive model for TAVR-related coronary obstruction in native aortic stenosis.

Methods

Preprocedure computed tomography and fluoroscopy images of patients in whom TAVR caused coronary artery obstruction were collected. Central laboratories made measurements, which were compared with unobstructed patients from a single-center database. A multivariate model was developed and validated against a 1:1 propensity-matched subselection of the unobstructed cohort.

Results

Sixty patients with angiographically confirmed coronary obstruction and 1,38

SUBMITTER: Khan JM 

PROVIDER: S-EPMC9991077 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature