Hospital-level variation in genetic testing in children's hospitals' neonatal intensive care units from 2016 to 2021.

ABSTRACT:

Purpose

This study aimed to examine variation in genetic testing between neonatal intensive care units (NICUs) across hospitals over time.

Methods

We performed a multicenter large-scale retrospective cohort study using NICU discharge data from the Pediatric Hospital Information System database between 2016 and 2021. We analyzed the variation in the percentage of NICU patients who had any genetic testing across hospitals and over time. We used a multivariable multilevel logistic regression model to investigate the potential association between patient characteristics and genetic testing.

Results

The final analysis included 207,228 neonates from 38 hospitals. Overall, 13% of patients had at least 1 genetic test sent, although this varied from 4% to 50% across hospitals.

SUBMITTER: Callahan KP 

PROVIDER: S-EPMC9991964 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature