Indoor environmental exposures and obstructive lung disease phenotypes among children with asthma living in poor urban neighborhoods.

ABSTRACT:

Background

Air trapping is an obstructive phenotype that has been associated with more severe and unstable asthma in children. Air trapping has been defined using pre- and postbronchodilator spirometry. The causes of air trapping are not completely understood. It is possible that environmental exposures could be implicated in air trapping in children with asthma.

Objective

We investigated the association between indoor exposures and air trapping in urban children with asthma.

Methods

Children with asthma aged 5 to 17 years living in Baltimore and enrolled onto the Environmental Control as Add-on Therapy for Childhood Asthma study were evaluated for air trapping using spirometry. Aeroallergen sensitization was assessed at baseline, and spirometry was performed at 0, 3,

SUBMITTER: Grant T 

PROVIDER: S-EPMC9992008 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature