How I treat recurrent pediatric high-grade glioma (pHGG): a Europe-wide survey study.

ABSTRACT:

Purpose

As there is no standard of care treatment for recurrent/progressing pediatric high-grade gliomas (pHGG), we aimed to gain an overview of different treatment strategies.

Methods

In a web-based questionnaire, members of the SIOPE-BTG and the GPOH were surveyed on therapeutic options in four case scenarios (children/adolescents with recurrent/progressing HGG).

Results

139 clinicians with experience in pediatric neuro-oncology from 22 European countries participated in the survey. Most respondents preferred further oncological treatment in three out of four cases and chose palliative care in one case with marked symptoms. Depending on the case, 8-92% would initiate a re-resection (preferably hemispheric pHGG), combined with molecular diagnostics. Throughout all ca

SUBMITTER: Perwein T 

PROVIDER: S-EPMC9992031 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature