L-Shaped Heterobidentate Imidazo[1,5-a]pyridin-3-ylidene (N,C)-Ligands for Oxidant-Free Au^I /Au^III Catalysis.

ABSTRACT: In the last decade, major advances have been made in homogeneous gold catalysis. However, Au^I /Au^III catalytic cycle remains much less explored due to the reluctance of Au^I to undergo oxidative addition and the stability of the Au^III intermediate. Herein, we report activation of aryl halides at gold(I) enabled by NHC (NHC=N-heterocyclic carbene) ligands through the development of a new class of L-shaped heterobidentate ImPy (ImPy=imidazo[1,5-a]pyridin-3-ylidene) N,C ligands that feature hemilabile character of the amino group in combination with strong σ-donation of the carbene center in a rigid conformation, imposed by the ligand architecture. Detailed characterization and control studies reveal key ligand features for Au^I /Au^III

SUBMITTER: Gao P 

PROVIDER: S-EPMC9992098 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature