Does a One Health approach to human African trypanosomiasis control hasten elimination? A stochastic compartmental modeling approach.

ABSTRACT:

Background

. In response to large strides in the control of human African trypanosomiasis (HAT), in the early 2000s the WHO set targets for elimination of both the gambiense (gHAT) and rhodesiense (rHAT) forms as a public health (EPHP) problem by 2020, and elimination of gHAT transmisson (EOT) by 2030. While global EPHP targets have been met, and EOT appears within reach, current control strategies may fail to achieve gHAT EOT in the presence of animal reservoirs, the role of which is currently uncertain. Furthermore, rHAT is not targeted for EOT due to the known importance of animal reservoirs for this form.

Methods

. To evaluate the utility of a One Health approach to gHAT and rHAT EOT, we built and parameterized a compartmental stochastic model, using the Institute for Di

SUBMITTER: Meisner J 

PROVIDER: S-EPMC9992224 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature