Anatomically informed multi-level fiber tractography for targeted virtual dissection.

ABSTRACT:

Objectives

Diffusion-weighted MRI can assist preoperative planning by reconstructing the trajectory of eloquent fiber pathways, such as the corticospinal tract (CST). However, accurate reconstruction of the full extent of the CST remains challenging with existing tractography methods. We suggest a novel tractography algorithm exploiting unused fiber orientations to produce more complete and reliable results.

Methods

Our novel approach, referred to as multi-level fiber tractography (MLFT), reconstructs fiber pathways by progressively considering previously unused fiber orientations at multiple levels of tract propagation. Anatomical priors are used to minimize the number of false-positive pathways. The MLFT method was evaluated on synthetic data and in vivo data by reconstruc

SUBMITTER: Zhylka A 

PROVIDER: S-EPMC9992235 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature