Associations of body size with all-cause and cause-specific mortality in healthy older adults.

ABSTRACT: In the general population, body mass index (BMI) and waist circumference are recognized risk factors for several chronic diseases and all-cause mortality. However, whether these associations are the same for older adults is less clear. The association of baseline BMI and waist circumference with all-cause and cause-specific mortality was investigated in 18,209 Australian and US participants (mean age: 75.1 ± 4.5 years) from the ASPirin in Reducing Events in the Elderly (ASPREE) study, followed up for a median of 6.9 years (IQR: 5.7, 8.0). There were substantially different relationships observed in men and women. In men, the lowest risk of all-cause and cardiovascular mortality was observed with a BMI in the range 25.0-29.9 kg/m² [HR_{25-29.9 vs 21-24.9 kg/m}²

SUBMITTER: Carr PR 

PROVIDER: S-EPMC9992380 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature