Extracellular vesicles as potential biomarkers and treatment options for liver failure: A systematic review up to March 2022.

ABSTRACT:

Introduction

Extracellular vesicles (EVs) carrying functional cargoes are emerging as biomarkers and treatment strategies in multiple liver diseases. Nevertheless, the potential of EVs in liver failure remains indistinct. In this systematic review, we comprehensively analyzed the potential of EVs as biomarkers of liver failure and the therapeutic effects and possible mechanisms of EVs for liver failure.

Methods

We conducted a systematic review by comprehensively searching the following electronic databases: PubMed, Web of Science, Embase and Cochrane Central Register of Controlled Trials from inception to March 2022. The used text words (synonyms and word variations) and database-specific subject headings included "Extracellular Vesicles", "Exosomes", "Liver Failure", "Liver

SUBMITTER: Lu W 

PROVIDER: S-EPMC9992400 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature