Contemporary real-world radiotherapy outcomes of unresected locally advanced non-small cell lung cancer.

ABSTRACT:

Background

Radiotherapy (RT) is used as monotherapy in poor performance patients with unresected locally advanced non-small cell lung cancer (LA-NSCLC), but their outcomes are not well-described. As novel therapies are increasingly considered in this space, it is important to understand contemporary outcomes of RT alone. Here, in this retrospective cohort study we analyzed LA-NSCLC outcomes of RT alone in Ontario, Canada, and contrasted them against those of standard of care (SoC) treatment of concurrent chemo-radiotherapy (cCRT).

Methods

Ontario provincial databases were searched through the Institute of Clinical Evaluative Sciences (IC/ES) for stage III NSCLC patients diagnosed between 2007 and 2017. Surgical patients were excluded, and all patients that received RT withou

SUBMITTER: Gouran-Savadkoohi M 

PROVIDER: S-EPMC9992560 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature