Real-world experience of arbidol for Omicron variant of SARS-CoV-2.

ABSTRACT:

Background

At a crucial time with the rapid spread of Omicron severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus variant globally, we conducted a study to evaluate the efficacy and safety of arbidol tablets in the treatment of this variant.

Methods

From Mar 26 to April 26, 2022, we conducted a prospective, open-labeled, controlled, and investigator-initiated trial involving adult patients with confirmed Omicron variant infection. Patients with asymptomatic or mild clinical status were stratified 1:2 to receive either standard-of-care (SOC) or SOC plus arbidol tablets (oral administration of 200 mg per time, three times a day for 5 days). The primary endpoint was the negative conversion rate within the first week.

Results

A total of 367 patients were en

SUBMITTER: Zhao J 

PROVIDER: S-EPMC9992600 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature