Lung cancer with air lucency: a systematic review and clinical management guide.

ABSTRACT:

Background

Lung cancers with air lucency are poorly understood, often recognized only after substantial progression.

Methods

From a systematic review (PubMed and EMBASE, 2000-2022, terms related to cystic, cavitary, bulla, pseudocavitary, bubble-like, date 10-30-2022) 49 studies were selected using broad inclusion criteria (case series of ≥10 cases up to trials and reviews). There was no source of funding. Primary evidence relevant to clinical management issues was assembled. Because data was available only from heterogeneous retrospective case series, meta-analysis and formal risk-of-bias assessment was omitted. A framework was developed to guide clinical management based on the available data.

Results

Demographic, smoking and histologic differences suggest that cyst

SUBMITTER: Detterbeck FC 

PROVIDER: S-EPMC9992605 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature