Impaired exercise capacity in individuals with non-obstructive small airway dysfunction.

ABSTRACT:

Background

Whether individuals with non-obstructive spirometry-defined small airway dysfunction (SAD) have impaired exercise capacity is unclear, particularly in never-smokers. This study clarifies the degree of impaired exercise capacity and its potential cause in individuals with non-obstructive SAD.

Methods

This community-based, multiyear cross-sectional study analyzed data collected in Guangdong, China from 2012-2019 by the National Science and Technology Support Plan Program. Measurements of exercise capacity [peak work rate and peak oxygen uptake ( V˙O2peak )] in participants with non-obstructive spirometry-defined SAD (n=157) were compared with those in controls (n=85) and Global Initiative for Chronic Obstructive Lung Disease (GOLD) I patients (n=239). Subgroup analy

SUBMITTER: Deng Z 

PROVIDER: S-EPMC9992616 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature