Estimating human mobility in Holocene Western Eurasia with large-scale ancient genomic data.

ABSTRACT: The recent increase in openly available ancient human DNA samples allows for large-scale meta-analysis applications. Trans-generational past human mobility is one of the key aspects that ancient genomics can contribute to since changes in genetic ancestry-unlike cultural changes seen in the archaeological record-necessarily reflect movements of people. Here, we present an algorithm for spatiotemporal mapping of genetic profiles, which allow for direct estimates of past human mobility from large ancient genomic datasets. The key idea of the method is to derive a spatial probability surface of genetic similarity for each individual in its respective past. This is achieved by first creating an interpolated ancestry field through space and time based on multivariate statistics and Gaussian pro

SUBMITTER: Schmid C 

PROVIDER: S-EPMC9992830 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature