Different clinical characteristics and outcomes of hypertrophic cardiomyopathy with and without hypertension: seeking the truth.

ABSTRACT:

Objective

To determine the different clinical characteristics and outcomes of hypertrophic cardiomyopathy (HCM) patients with and without hypertension (HT).

Methods

A total of 696 HCM patients were included in this study and all HCM diagnoses were confirmed by the genetic test. Patients were analyzed separately in the septal reduction therapy (SRT) cohort and the non-SRT cohort. The primary endpoint was cardiovascular death and the secondary endpoint was all-cause death. Outcome analyses were conducted to evaluate the associations between HT and outcomes in HCM. Medications before enrollment and at discharge were collected in the post-hoc analyses.

Results

HCM patients without HT were younger, had a lower body mass index, were more likely to have a family histo

SUBMITTER: Zhang Y 

PROVIDER: S-EPMC9992951 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature