Effect of renal denervation for patients with isolated systolic hypertension: a systematic review and meta-analysis.

ABSTRACT:

Background

Renal denervation (RDN) is a promising treatment based on catheter intervention for patients with refractory hypertension. However, the effect in patients with isolated systolic hypertension (ISH) remains controversial. The aim of this meta-analysis was to determine the blood pressure lowing effect of RDN in patients with ISH compared with combined systolic/diastolic hypertension (CH) patients.

Methods

PubMed, Embase, Cochrane and ClinicalTrials.gov were searched for prospective clinical studies that included RDN. The outcomes of interest were the change of 24-hour ambulatory systolic blood pressure (SBP) from baseline. We used the fixed effects model to calculate weighted mean difference (WMD) with 95% confidence interval (CI).

Results

Six trials were incl

SUBMITTER: Li L 

PROVIDER: S-EPMC9992953 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature