A 30-Minute Spontaneous Breathing Trial Misses Many Children Who Go On to Fail a 120-Minute Spontaneous Breathing Trial.

ABSTRACT:

Background

The optimal length of spontaneous breathing trials (SBTs) in children is unknown.

Research questions

What are the most common reasons for SBT failure in children, and when do they occur? Can clinical parameters at the 30-min mark of a 120-min SBT predict outcome?

Study design and methods

We performed a secondary analysis of a clinical trial in pediatric ARDS, in which 2-h SBTs are conducted daily. SBT failure is based on objective criteria, including esophageal manometry for effort of breathing, categorized as passage, early failure (≤ 30 min), or late failure (30-120 min). Spirometry was used to calculate respiratory rate (RR), tidal volume (Vt), and rapid shallow breathing index (RSBI), in addition to pulse oximetry and capnography. Predictive models eval

SUBMITTER: Knox KE 

PROVIDER: S-EPMC9993340 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature