Comparison of statins for primary prevention of cardiovascular disease and persistent physical disability in older adults.

ABSTRACT:

Purpose

Recent epidemiological evidence has suggested that use of lipid-lowering medications, particularly statins, was associated with reduced cardiovascular disease (CVD) events and persistent physical disability in healthy older adults. However, the comparative efficacy of different statins in this group remains unclear. This study aimed to compare different forms of statins in their associations with CVD and physical disability in healthy older adults.

Methods

This post hoc analysis included data from 5981 participants aged ≥ 70 years (≥ 65 if US minorities; median age:74.0) followed for a median of 4.7 years, who had no prior CVD events or physical disability and reported using a statin at baseline. The incidence of the composite and components of major adverse cardiova

SUBMITTER: Zhou Z 

PROVIDER: S-EPMC9993349 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature