Factors related to the mortality risk of severe hand, foot, and mouth diseases (HFMD): a 5-year hospital-based survey in Guangxi, Southern China.

ABSTRACT:

Background

To understand the factors influencing clinical outcomes of severe hand, foot, and mouth diseases (HFMD), and to provide scientific evidence for reducing the mortality risk of severe HFMD.

Methods

From 2014 to 2018, children diagnosed with severe HFMD cases in Guangxi, China, were enrolled in this hospital-based study. The epidemiological data obtained through face-to-face interviews with the parents and guardians. Univariate and multivariate logistics regression models were used to analyze the factors influencing the clinical outcomes of severe HFMD. The impact of the EV-A71 vaccination on inpatient mortality was analyzed by a comparison approach.

Results

A total of 1565 severe HFMD cases were enrolled in this survey, including 1474 (94.19%) survival cases

SUBMITTER: Peng Y 

PROVIDER: S-EPMC9993373 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature