Geographical origin of Plasmodium vivax in the Hainan Island, China: insights from mitochondrial genome.

ABSTRACT:

Background

Hainan Province, China, has been an endemic region with high transmission of Plasmodium falciparum and Plasmodium vivax. Indigenous malaria caused by P. vivax was eliminated in Hainan in 2011, while imported vivax malaria remains. However, the geographical origin of P. vivax cases in Hainan remains unclear.

Methods

Indigenous and imported P. vivax isolates (n = 45) were collected from Hainan Province, and the 6 kb mitochondrial genome was obtained. Nucleotide (π) and haplotype (h) diversity were estimated using DnaSP. The numbers of synonymous nucleotide substitutions per synonymous site (d_S) and nonsynonymous nucleotide substitutions per nonsynonymous site (d_N) were calculated using the SNAP program. Arlequin software was used to estimate th

SUBMITTER: Li Y 

PROVIDER: S-EPMC9993381 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature