A Retrospective Analysis of the Effects of Time on Compliance and Driving Pressures in ARDS.

ABSTRACT:

Background

The evolution of compliance and driving pressure in ARDS and the effects of time spent on noninvasive respiratory support prior to intubation have not been well studied. We conducted this study to assess the effect of the duration of noninvasive respiratory support prior to intubation (ie, noninvasive ventilation [NIV], high-flow nasal cannula [HFNC], or a combination of NIV and HFNC) on static compliance and driving pressure and retrospectively describe its trajectory over time for COVID-19 and non-COVID-19 ARDS while on mechanical ventilation.

Methods

This is a retrospective analysis of prospectively collected data from one university-affiliated academic medical center, one rural magnet hospital, and 3 suburban community facilities. A total of 589 subjects were

SUBMITTER: Jagan N 

PROVIDER: S-EPMC9993514 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature