Temperature-induced embryonic diapause in chickens is mediated by PKC-NF-κB-IRF1 signaling.

ABSTRACT:

Background

Embryonic diapause (dormancy) is a state of temporary arrest of embryonic development that is triggered by unfavorable conditions and serves as an evolutionary strategy to ensure reproductive survival. Unlike maternally-controlled embryonic diapause in mammals, chicken embryonic diapause is critically dependent on the environmental temperature. However, the molecular control of diapause in avian species remains largely uncharacterized. In this study, we evaluated the dynamic transcriptomic and phosphoproteomic profiles of chicken embryos in pre-diapause, diapause, and reactivated states.

Results

Our data demonstrated a characteristic gene expression pattern in effects on cell survival-associated and stress response signaling pathways. Unlike mammalian diapause, mT

SUBMITTER: Ren J 

PROVIDER: S-EPMC9993608 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature