Thrombosis and bleeding in patients with COVID-19 requiring extracorporeal membrane oxygenation: a systematic review and meta-analysis.

ABSTRACT:

Background

Extracorporeal membrane oxygenation (ECMO) and COVID-19 significantly impact the coagulation system. A systematic review and meta-analysis were performed to explore the prevalence of thrombotic and bleeding events in patients with COVID-19 supported with ECMO, summarize anticoagulation regimens, and guide future research.

Methods

Cochrane, EMBASE, Scopus, and PubMed were searched for studies examining thrombosis and bleeding in patients with COVID-19 requiring ECMO. The primary outcomes were the prevalences of different types of hemorrhage and thrombosis. The pooled estimated rates and relative risk (RR) were calculated to summarize the outcomes.

Results

Twenty-three peer-reviewed studies involving 6878 subjects were included. For thrombotic events, the pre

SUBMITTER: Jin Y 

PROVIDER: S-EPMC9993729 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature