Inhaled Medication Use in Smokers With Normal Spirometry.

ABSTRACT:

Background

The objective of our study was to identify variables associated with inhaled medication use in smokers with normal spirometry (GOLD-0) and to examine the association of inhaled medication use with development of exacerbations and obstructive spirometry in the future.

Methods

We performed a retrospective multivariable analysis of GOLD-0 subjects identified in data from the COPDGene study to examine factors associated with medication use. Five categories were identified: (1) no medications, (2) short-acting bronchodilator, (3) long-acting bronchodilator; long-acting muscarinic antagonists and/or long-acting β agonist, (4) inhaled corticosteroids (ICS) with or without long-acting bronchodilator, and (5) dual bronchodilator with ICS. Sensitivity analysis was performed

SUBMITTER: R Arnold N 

PROVIDER: S-EPMC9993991 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature