Direct Extubation to High-Flow Nasal Cannula versus Noninvasive Ventilation in Obese Subjects.

ABSTRACT:

Background

Patients who are obese have a higher risk of acute respiratory failure after extubation in the ICU. This study aimed to compare the extubation of subjects who were critically ill and obese to high-flow nasal cannula (HFNC) versus noninvasive ventilation (NIV) to determine whether HFNC can aid in reducing postextubation respiratory failure and the re-intubation rate.

Methods

In this randomized controlled trial, subjects who were obese, defined as individuals with a body mass index ≥ 30 kg/m², were randomly assigned to receive HFNC (n = 60) versus 60 subjects treated with NIV applied immediately after extubation. The primary outcome was the incidence of postextubation respiratory failure and re-intubation rate within 72 h. Secondary outcomes includ

SUBMITTER: Magdy DM 

PROVIDER: S-EPMC9994274 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature